CANYON-1: Topline Data and Upcoming Events

CRB-913 in Obesity

CANYON-1: Topline Data and Upcoming Events

CRB-913 demonstrated a favorable safety profile with mean weight loss of up to 5% at 12 weeks with no plateau observed. These data support CRB-913’s potential to establish a new class of non-incretin obesity medicines. The data was selected for a late-breaking presentation at ObesityWeek® 2026

CRB-913 is a once-daily, highly peripherally restricted oral CB1 inverse agonist designed as a potential non-incretin approach to weight loss and long-term weight management.

Explore the Canyon-1 data including the press release, corporate presentation, KOL webcast, media coverage and upcoming scientific conferences.

Upcoming

Presentations and Events

CRB-913 at Obesity Week 2026

CANYON-1 data have been selected for a late-breaking presentation at ObesityWeek 2026, taking place November 14–17 in Washington, DC.

Featured Coverage and Interviews

Explore recent coverage and conversations about CANYON-1, CRB-913 and the evolving treatment landscape in obesity.

Featured Article

Trial breakthrough for weight-loss drug with fewer side effects

Financial Times

Ahead of CANYON-1: CRB-913 and its potential in obesity

Ahead of the CANYON-1 topline data readout, Corbus CEO Yuval Cohen discussed CRB-913 and its potential in obesity on the Molecules and Minerals podcast.